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Abstract #2351

Comparison of single- and multi-echo PRF-shift thermometry and method for penalized-likelihood multi-echo temperature reconstruction

Pooja Gaur 1,2 and William A Grissom 2,3

1 Chemical and Physical Biology, Vanderbilt University, Nashville, Tennessee, United States, 2 Institute of Imaging Science, Vanderbilt University, Nashville, Tennessee, United States, 3 Biomedical Engineering, Vanderbilt University, Nashville, Tennessee, United States

Single echo scans with low bandwidth are commonly used in guiding thermal therapies, but are susceptible to distortions caused by both heating-induced and static off-resonance effects, resulting in distorted temperature maps. We show that multi-echo scans with higher bandwidths can alleviate distortions without sacrificing temperature SNR. A penalized-likelihood temperature reconstruction algorithm is also proposed for multi-echo thermometry, that produces more accurate temperature maps than previous methods, and does not require phase unwrapping.

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