Abstract #2187
Relative Signal Loss from Fat Using In- and Out-of-phase Images for Indicating Renal Health
Joshua D Kaggie 1 , Vivian S Lee 1 , and Glen R Morrell 1
1
Utah Center for Advanced Imaging Research,
Radiology, University of Utah, Salt Lake City, UT,
United States
A recent study in diabetic mice suggests a correlation
between renal cortical fat content and severity of renal
disease. We retrospectively evaluated the fat content of
kidneys in 14 human subjects with varying degrees of
renal failure ranging from normal renal function to
dialysis dependence, based on in- and out-of-phase
T1-weighted axial images of the kidneys. Correlation
between fat content measured with the
in-phase/out-of-phase images and the body mass index
(BMI) or estimated glomerular filtration rate (eGFR) was
investigated. We find no significant correlation between
renal fat content and severity of renal disease in
humans with diabetic nephropathy.
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