Abstract #2160
Volumetric T1 Mapping of liver parenchyma at 3 T: Diagnosing Liver Cirrhosis
Niklas Verloh 1 , Claudia Fellner 1 , Michael Haimerl 1 , Mona Schlabeck 1 , Miriam Rabea Kukach 2 , Marcel D. Nickel 2 , Christian Stroszczynski 1 , and Philipp Wiggermann 1
1
Department of Radiology, University Hospital
Regensburg, Regensburg, Germany,
2
MR
Applications Development, Siemens AG, Healthcare Sector,
Erlangen, Germany
The purpose of the study was to assess the ability of
volumetric T1 mapping of Gd-EOB-DTPA-enhanced MRI to
detect liver cirrhosis. Mean T1 relaxation time of the
whole liver parenchyma was used to calculate the
reduction rate between plain and enhanced T1 relaxation
time. Patients with and without liver cirrhosis were
analyzed regarding their reduction rate. The reduction
rate of the whole liver was significantly (p ≤ 0.001)
lower in patients with liver cirrhosis (35% 8%)
compared to patients with normal liver function (58%
6%). The evaluation of changes in T1 mapping of liver
parenchyma in Gd-EOB-DTPA-enhanced images may serve as a
useful new, non-invasive technique to quantify liver
cirrhosis
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