Predicting Final Infarct Volume at One Week Post Ischemic Stroke: Recanalization and Baseline Infarct Volume are Important Parameters for Early Infarct Estimation
Mark Krongold 1,2 , Mohammed Almekhlafi 1,2 , Andrew Demchuck 1,3 , Richard Frayne 1,2 , and Armin Eilaghi 1,2
Department of Radiology and Clinical
Neurosciences, Hotchkiss Brain Institute, University of
Calgary, Calgary, Alberta, Canada,
Family MR Centre, Foothills Medical Centre, Calgary,
Stroke Program, Foothills Medical Centre, Calgary,
Our goal was to characterize infarct volume evolution
over time with focus on the first 30 days post stroke.
We screened 964 ischemic stroke patients and included 59
patients who had baseline DWI infarction and ≥2 FLAIR
follow up imaging sessions. We show that the final
infarct volume can be predicted after the first week.
Recanalization status and baseline infarct volume
significantly effect infarct expansion pattern and
infarct volume size. These findings can potentially
maximize recruitment in clinical trials, decrease needed
follow up imaging sessions, and improve stroke
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