Abstract #2040
Comparison of plaque imaging and luminal stenosis to discriminate clinical presentation in middle cerebral artery disease
Wenjia Peng 1,2 , Zhongzhao Teng 2,3 , Adam J Brown 4 , Jianmin Yuan 2 , Qi Liu 1 , Jonathan H Gillard 2 , and Jianping Lu 1
1
Department of Radiology, Changhai Hospital,
Shanghai, Shanghai, China,
2
University
Department of Radiology, University of Cambridge,
Cambridge, United Kingdom,
3
Department of
Engineering, University of Cambridge, Cambridge, United
Kingdom,
4
Division
of Cardiovascular Medicine, University of Cambridge,
Cambridge, United Kingdom
Intracranial atherosclerosis is a major substrate for
stroke, accounting for 5-10% of strokes in western
societies and 33-55% of strokes in Asian populations.
Plaque wall MR imaging is capable of depicting high risk
morphological and compositional features, such as
intraplaque hemorrhage and fibrous cap rupture. However,
it is unclear if this technique could provide
complementary information to lumen stenosis to
discriminate clinical presentation in patients with
middle cerebral artery (MCA) atherosclerotic disease.
The result obtained in this study indicated that
high-resolution MCA plaque wall imaging using 2D Turbo
MR sequences provided limited additional value to
luminal stenosis.
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