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Abstract #2032

Increase of fractional anisotropy in contralateral thalamic motor nucleus in MCA stroke using tract-based segmentation method

Yi-Hsiu Hsiao 1 , Yung-Chieh Chen 2 , Cheng-Yu Chen 1,3 , Shih-Wei Chiang 4,5 , Hsiao-Wen Chung 5 , Ping-Huei Tsai 1 , Ming-Chung Chou 6 , Hung-Wen Kao 4 , and Chao-Ying Wang 4

1 Department of Medical Imaging and Imaging Research Center, Taipei Medical University Hospital, Taipei Medical University, Taipei, Taiwan, 2 Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei, Taiwan, 3 Graduate Institue of Clinical Medicine, Taipei Medical University, Taipei, Taiwan, 4 Department of Radiology, Tri-Service General Hospital, Taipei, Taiwan, 5 Graduate Institute of Biomedical Electrics and Bioinformatics, National Taiwan University, Taipei, Taiwan, 6 Department of Medical Imaging and Radiological Sciences, Kaohsiung Medical University, Kaohsiung, Taiwan

Thalamus plays a pivot role in the process of rebuilding the circuitry after MCA stroke by neuro-adaptation called plasticity. One previous study has demonstrated that, by using diffusion tensor imaging (DTI), an increase in mean diffusivity in thalamus was shown after MCA infarct but fractional anisotropy (FA) remained unchanged. This study was limited by a lack of investigating the individual thalamic nucleus. Therefore, we aim to evaluate the changes of FA in the motor-sensory-related thalamic nuclei (VA, VL and VPL) in patients with MCA ischemic stroke at both acute and chronic stages using tract-based segmentation method.

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