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Abstract #1883

Modeling focal cortical dysplasia lesions using diffusion of gadolinium-DTPA in gel phantoms

Quentin Duch 1,2 , Giulio Gambarota 1,2 , Isabelle Merlet 1,2 , Oscar Acosta 1,2 , and Herv Saint-Jalmes 1,2

1 Universit de Rennes 1 - LTSI, Rennes, Bretagne, France, 2 INSERM, UMR 1099, Rennes, France

Many disorders such as multiple sclerosis or focal cortical dysplasia (FCD) require the use of MRI to precisely delineate size limited lesions. Optimizing MRI sequences to enhance the contrast between healthy and pathological tissues is necessary. In addition, improving brain images postprocessing algorithms of pathological subjects where usual assumptions are void is an important task. For this purpose, it is of primary interest to develop test objects able to mimic the aspect of certain brain lesions. This will allow the optimization for both MRI sequences and postprocessing algorithms. In this work, we present a useful test object for sequences optimization.

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