Abstract #1849
Quantitative intra-tumoral susceptibility signal in grading brain astrocytomas with susceptibility-weighted imaging
Tzu-Chao Chuang 1 , Wan-Pin Shui 1 , Hsiao-Wen Chung 2 , and Ping-Hong Lai 3,4
1
Electrical Engineering, National Sun Yat-Sen
University, Kaohsiung, Taiwan, Taiwan,
2
Electrical
Engineering, National Taiwan University, Taipei, Taiwan,
3
Radiology,
Kaohsiung Veteran General Hospital, Kaohsiung, Taiwan,
4
School
of Medicine, National Yang-Ming University, Taipei,
Taiwan
Using susceptibility weighted imaging (SWI), a
quantitative measurement of volumetric percentage of
intra-tumoral susceptibility signal (ITSS) was reported
in order to provide useful information in tumor grading
of brain astrocytomas at 1.5 T. High-resolution SWI of
43 patients, including 35 high-grade (WHO grade III and
IV) and 8 low-grade (all WHO grade II), were analyzed in
this study. With the suggested threshold for ITSS
evaluation, significance difference between the ITSS
percentages of high-grade and low-grade astrocytomas was
found (p<0.01) with an area under ROC curve of 0.89,
rendering this quantitative index as a helpful
classifier on discrimination of tumor grade.
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