Meeting Banner
Abstract #1849

Quantitative intra-tumoral susceptibility signal in grading brain astrocytomas with susceptibility-weighted imaging

Tzu-Chao Chuang 1 , Wan-Pin Shui 1 , Hsiao-Wen Chung 2 , and Ping-Hong Lai 3,4

1 Electrical Engineering, National Sun Yat-Sen University, Kaohsiung, Taiwan, Taiwan, 2 Electrical Engineering, National Taiwan University, Taipei, Taiwan, 3 Radiology, Kaohsiung Veteran General Hospital, Kaohsiung, Taiwan, 4 School of Medicine, National Yang-Ming University, Taipei, Taiwan

Using susceptibility weighted imaging (SWI), a quantitative measurement of volumetric percentage of intra-tumoral susceptibility signal (ITSS) was reported in order to provide useful information in tumor grading of brain astrocytomas at 1.5 T. High-resolution SWI of 43 patients, including 35 high-grade (WHO grade III and IV) and 8 low-grade (all WHO grade II), were analyzed in this study. With the suggested threshold for ITSS evaluation, significance difference between the ITSS percentages of high-grade and low-grade astrocytomas was found (p<0.01) with an area under ROC curve of 0.89, rendering this quantitative index as a helpful classifier on discrimination of tumor grade.

This abstract and the presentation materials are available to members only; a login is required.

Join Here