Meeting Banner
Abstract #1848

Comparison of standardized and normalized rCBV to differentiate astrocytic brain tumors

Mona M Al-Gizawiy 1 , Melissa A Prah 1 , Peter S LaViolette 1 , Wade M Mueller 2 , and Kathleen M Schmainda 1,3

1 Radiology, Medical College of Wisconsin, Milwaukee, Wisconsin, United States, 2 Neurosurgery, Medical College of Wisconsin, Milwaukee, Wisconsin, United States, 3 Biophysics, Medical College of Wisconsin, Wisconsin, United States

Perfusion imaging is an invaluable tool for brain tumor characterization. Relative cerebral blood volume (rCBV) maps provide insight into brain tumor vascularization. The purpose of this study was to compare standardized (sRCBV) and normalized (nRCBV) measures in conjunction with intraoperative navigation and tissue diagnosis for astrocytoma grading. Preoperative imaging was co-registered to intraoperative surgical navigation scans, and rCBV values were calculated for each tissue sampling site. sRCBV showed greater potential in differentiating astrocytic tumors than nRCBV. This study highlights the importance of perfusion imaging in brain tumor characterization.

This abstract and the presentation materials are available to members only; a login is required.

Join Here