Abstract #1841
Cortical Phase Shifts in Healthy Aging at 7 Tesla
Mathijs Buijs 1 , Nhat Trung Doan 2 , Sanneke van Rooden 1 , Maarten Versluis 1 , Julien Milles 2 , Jeroen van der Grond 1 , and Mark van Buchem 1
1
Radiology, Leiden University Medical Center,
Leiden, Netherlands,
2
Division
of Image Processing (LKEB), Leiden University Medical
Center, Leiden, Netherlands
In recent years phase imaging has become available as a
method of measuring iron in vivo. Scanning at 7 Tesla
has increased the usability of phase images for smaller
structures. The aim of this study was to investigate the
appearance of phase contrast in the cerebral cortex in
normal aging. We scanned three different age groups and
measured cortical phase values using an in-house
developed tool. Our study shows an increase in
paramagnetic phase shift with age in the cerebral cortex
of healthy subjects at 7T. The most significant increase
in phase shift is seen between middle and old age.
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