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Abstract #1815

Analysis of Group ICA functional connectivity of task-driven fMRI: application to language processes in adults with auditory deprivation

Antonio Napolitano 1 , Martina Andellini 1 , Vittorio Cannat 1 , Francesco Randisi 2 , Bruno Bernardi 2 , Marianna Castrataro 3 , Giovanni Pezzullo 3 , Pasquale Rinaldi 3 , Maria Cristina Caselli 3 , and Laura Barca 3

1 Enterprise Risk Management, Bambino Ges children's hospital, Rome, Lazio, Italy, 2 Unit of Neuroradiology, Bambino Ges children's hospital, Rome, Lazio, Italy, 3 Institute of Cognitive Sciences and Technologies, National Research Council, Rome, Lazio, Italy

Task-driven fMRI has been used to investigate brain networks during a reading process task in deaf signer, deaf using spoken language and control subjects; The study originate from the hypothesis of the existence of a very basic network that plays the role of general framework for language processing. The group specific ICs were identified by ICA and dual regression technique. Interestingly, we found differences in those networks which has been recognized implicated to auditory and to cognition-language processes.

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