In vivo cerebral perfusion territory and watershed zone delineation in healthy volunteers using ASL, DSC-, and DCE-MRI.

We used timing parameters from a variety of perfusion-based MR imaging techniques (ASL, DSC-, and DCE-MRI) in order to investigate the major hemispheric, subcortical, and cerebellar perfusion territories and intervening watershed zones in a group of healthy volunteers with non-variant circle of Willis anatomy. An MNI space atlas was then constructed delineating a probabilistic map of these perfusion territories, the first time such a map has been produced from in vivo data. Such information is invaluable to those investigating links between neurovascular hemodynamics and other neurological conditions.

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