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Abstract #1728

Manganese Enhanced MRI Assay of Spinal Cord Functional Connectivity

Xiaowei Zhang 1 , Naomi Santa Maria 1 , Samuel Barnes 1 , and Russell E. Jacobs 1

1 Biological Imaging Center, Caltech, Pasadena, California, United States

Synopsis: After Mn++ injection into spinal cord (SC), MR hyperintensity spreads along the the SC and can be followed by MR imaging over time. MEMRI of intact SC pathways offers an alternative method to evaluate axonal outgrowth and the functional connectivity in cellular graft therapies of injured or diseased spinal cord.

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