Manganese Enhanced MRI Assay of Spinal Cord Functional Connectivity
Xiaowei Zhang 1 , Naomi Santa Maria 1 , Samuel Barnes 1 , and Russell E. Jacobs 1
Biological Imaging Center, Caltech,
Pasadena, California, United States
Synopsis: After Mn++ injection into spinal cord (SC), MR
hyperintensity spreads along the the SC and can be
followed by MR imaging over time. MEMRI of intact SC
pathways offers an alternative method to evaluate axonal
outgrowth and the functional connectivity in cellular
graft therapies of injured or diseased spinal cord.
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