Abstract #1715
Resting state functional connectivity in the human cervical spinal cord at 7 Tesla: preliminary results across healthy controls
Robert L Barry 1,2 , Seth A Smith 1,2 , Adrienne N Dula 1,2 , and John C Gore 1,2
1
Vanderbilt University Institute of Imaging
Science, Nashville, TN, United States,
2
Department
of Radiology and Radiological Sciences, Vanderbilt
University Medical Center, Nashville, TN, United States
Blood oxygenation level dependent signal fluctuations in
the resting brain have been exploited to characterize
low-frequency functional connectivity within specific
neural circuits. However, there have been no previous
rigorous reports of resting state correlations in the
spinal cord. In a cohort of healthy controls we observed
robust functional connectivity between left and right
ventrolateral (motor) horns, and left and right dorsal
(sensory) horns. No statistically significant
correlations are observed between spinal gray and white
matter, suggesting that observed correlations between
gray matter horns cannot be simply attributed to
spatially correlated physiological noise and likely
represent genuine connectivity.
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