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Abstract #1673

Fat Quantification with an Interleaved Bipolar Acquisition

Abraam S Soliman 1,2 , Curtis Wiens 3 , Trevor Wade 2,4 , Ann Shimakawa 5 , Terry M Peters 1,2 , and Charles A McKenzie 1,4

1 Biomedical Engineering, Western University, London, Ontario, Canada, 2 Imaging Research Laboratories, Robarts Research Institute, London, Ontario, Canada, 3 Radiology, University of Wisconsin, Madison, Wisconsin, United States, 4 Medical Biophysics, Western University, London, Ontario, Canada, 5 Global MR Applied Science Laboratory, GE Healthcare, Menlo Park, California, United States

Chemical-shift based multi gradient echo sequences have been widely used for water/fat separation. Typically, 6 unipolar readout gradients are applied over multiple shots in order to achieve optimal echo-spacing. Although single shot bipolar readout acquisition can offer optimal echo-spacing with shorter scan time, phase errors can significantly corrupt water/fat separation. To overcome this problem, a new interleaved bipolar acquisition is proposed. Accurate fat quantification is demonstrated in phantom and in-vivo experiments compared to the well-established unipolar sequence. The proposed bipolar acquisition scheme offers accurate fat fraction maps with shorter acquisitions and higher SNR efficiency compared to unipolar sequences.

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