Abstract #1422
Imaging oculomotor subsystems in the cerebellum at 7 Tesla
Melissa A Batson 1,2 , Natalia Petridou 3 , Dennis WJ Klomp 3 , Maarten A Frens 2 , and Sebastian FW Neggers 1
1
Brain Center Rudolf Magnus, UMC Utrecht,
Utrecht, Netherlands,
2
Neuroscience,
Erasmus Medical Center, Rotterdam, Zuid Holland,
Netherlands,
3
Imaging
Division, UMC Utrecht, Utrecht, Netherlands
Using an innovative combination of high-density
multi-unit surface coils, dual transmission, ROI
shimming and 3D parallel imaging at 7T it is possible to
clearly image the deep and complex structures and
functions of the cerebellum during various motor tasks,
including oculomotor tasks requiring eye tracking.
Results demonstrate superior functional localisation
within both oculomotor vermis and, when a cognitive
component is present, in both CrusI and CrusII. In
addition, BOLD signal strengths vary with the magnitude
of difficulty of the task for both motor and cognitive
components in a manner consistent with the changes in
firing patterns observed in animal cerebellum.
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