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Abstract #1172

Evaluation of bone quality in calcanei of young and postmenopausal women through ADC measurement

Silvia Capuani 1 , Rebuzzi Mauro 2 , Vincenzo Vinicola 3 , Umberto Sabatini 4 , and Marco Bozzali 5

1 Physics Department, CNR IPCF Roma "Sapienza " University, Rome, Rome, Italy, 2 Physics Department, Physics Department Sapienza University, Rome, Italy, 3 Rehabilitation Hospital, IRCCS Santa Lucia Foundation, Rome, Italy, 4 Radiology Department, IRCCS Santa Lucia Foundation, Rome, Italy, 5 Neuroimaging Laboratory, Santa Lucia Foundation, Rome, Italy

We have investigated water ADC changes in calcaneal cancellous bone of healthy subjects characterized by a large age range (22-69 y) and of osteopenic and osteoporotic patients at 3.0T employing DWI to quantify ADC and MRS techniques to quantify marrow fat content. ADC data from human calcanei shows the ability of diffusion measurement to obtain complementary information, compared to those provided by BMD, for investigating cancellous bone quality.

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