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Abstract #1171

Dynamic contrast enhanced MRI in patellofemoral pain syndrome: perfusion quantification of patellofemoral joint tissues

R.A. van der Heijden 1,2 , D.H.J. Poot 1,3 , E.E. Bron 1 , S. Klein 1 , J.A.N. Verhaar 4 , S.M.A. Bierma-Zeinstra 2,4 , M. van Middelkoop 2 , G. Kotek 1 , and E.H.G. Oei 1

1 Radiology, Erasmus Medical Center, Rotterdam, Netherlands, 2 General Practice, Erasmus Medical Center, Rotterdam, Netherlands, 3 Imaging Science and Technology, Delft University of Technology, Delft, Netherlands, 4 Orthopedics, Erasmus Medical Center, Rotterdam, Netherlands

Quantitative dynamic contrast-enhanced MRI (DCE-MRI) has the potential to advance the knowledge on the pathogenesis of bone diseases, such as PFPS, by measuring blood perfusion in bone quantitatively. However, there is no consensus regarding optimal analysis methods and pharmacokinetic model and there is no tailored method for the patellofemoral joint yet. We developed a tailored method for the patellofemoral joint. The results suggest that our tailored DCE-MRI protocol and post-processing tool successfully extract the dynamic contrast enhancement from the measurements, and thus can be used to study patellar blood perfusion.

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