Abstract #1107
DIFFUSION WEIGHTED MRI FOR RADIOTHERAPY TREATMENT OF LOCALLY ADVANCED CERVICAL CANCER TREATMENT RESPONSE ASSESSMENT USING DIFFERENT SEGMENTATION METHODS
Sren Haack 1 , Kari Tanderup 2 , Jesper Folsted Kallehauge 3 , Jacob Christian Lindegaard 2 , Erik Morre Pedersen 4 , and Sune Nrhj Jespersen 5,6
1
Dept. of Clinical Engineering, Aarhus
University Hospital, Aarhus, Denmark,
2
Dept.
of Oncology, Aarhus University Hospital, Aarhus,
Denmark,
3
Dept.
of Medical Physics, Aarhus University Hospital, Aarhus,
Denmark,
4
Dept.
of Radiology, Aarhus University Hospital, Aarhus,
Denmark,
5
CFIN/MindLab,
Aarhus University, Aarhus, Denmark,
6
Dept. of
Physics and Astronomy, Aarhus University, Aarhus,
Denmark
Diffusion weighted MRI has shown great potential in
diagnostic cancer imaging and may also have value for
monitoring tumor response during radiotherapy. Before DW
MRI can be used for monitoring treatment response
objective methods for segmentation of the hyper-intense
signal of the tumor at high b-value images should be
evaluated. This study evaluates three objective
segmentation methods used for monitoring treatment
response of twelve patients with advanced cervical
cancer treated with external beam radiotherapy followed
by brachytherapy. Segmented volume, resulting mean ADC
and histogram analysis are compared and evaluated.
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