Abstract #1012
Vessel-specific mapping of cerebral venous oxygenation of small veins
Lisa C. Krishnamurthy 1,2 and Hanzhang Lu 1
1
Advanced Imaging Research Center, UT
Southwester Medical Center, Dallas, TX, United States,
2
Dept.
of Bioengineering, University of Texas at Arlington,
Arlington, TX, United States
The ability to generate a small-vessel map of Yv may
help in better characterizing variations in venous
oxygenation across brain regions, identifying regions at
risk of ischemia attack or stroke, and may find
immediate applications in clinical conditions that
affect specific brain regions. The present study aims to
optimize a sequence called
T2-Relaxation-Under-Phase-Contrst (TRU-PC) MRI to
generate a complete Yv map of the vasculature in the
mid-sagittal brain, including small veins (1-2 mm in
caliber). The optimization includes removing an
eddy-current induced artifact to improve the Yv
quantification, adding additional scans to sensitize the
maps to more vessels, and merging these scans into a
single signal map for T2-fitting.
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