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Abstract #0991

HS8 saturation pulse train for first-pass myocardial perfusion imaging at 7T

Yuehui Tao 1 , Aaron T. Hess 1 , Graeme A. Keith 1 , Christopher T. Rodgers 1 , Alexander Liu 1 , Jane M. Francis 1 , Stefan Neubauer 1 , and Matthew D. Robson 1

1 University of Oxford Centre for Clinical Magnetic Resonance Research, University of Oxford, Oxford, United Kingdom

First-pass myocardial perfusion imaging is used clinically but would benefit from improvements, which might be expected at 7T due to higher SNR and longer T1. But major implementation challenges at 7T are found owing to the large B0&B1 variations across the heart, low peak B1, and SAR restrictions that make uniform saturation extremely difficult to achieve. We propose a train of four HS8 pulses for saturation in first-pass myocardial perfusion imaging at 7T, and compare it with previously proposed solutions in simulation and in-vivo experiments. We also present the first series of human first-pass myocardial perfusion images at 7T.

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