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Abstract #0858

Large matrix acquisition of a chemically fixed human embryo for construction of a 3D anatomical database

Yosuke Otake 1 , Takuma Yamada 1 , Katsumi Kose 1 , Tomoyuki Haishi 2 , and Shigehito Yamada 3

1 University of Tsukuba, Tsukuba, Ibaraki, Japan, 2 MRTechnology Inc., Ibaraki, Japan, 3 Kyoto University, Kyoto, Japan

3D MR images of a Carnegie Stage 22 (54-58 days post conception) chemically fixed human embryo were acquired with a 512x512x1024 image matrix using a solenoid coil in a 4.74 T magnetic field for construction of an anatomical database of the human embryos. Because the T2 of the mobile water protons was around 10 ms, a 3D gradient echo imaging sequence with a short echo-time (~6ms) was used. Anatomical structures of the embryo were clearly visualized at 30 microns cube voxel resolution. The result demonstrated feasibility of a 3D image database of human embryos at the 512x512x1024 image matrix.

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