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Abstract #0586

Functional target localization for neurosurgery: task-based fMRI versus resting state fMRI study

Halleh Ghaderi 1,2 , Abbas F. Sadikot 3,4 , and G. Bruce Pike 5,6

1 Biomedical Engineering, McGill University, Montreal, Quebec, Canada, 2 Brain Imaging Center, Montreal Neurological Institute, Montreal, Quebec, Canada, 3 Neurology and Neurosurgery, McGill University, Quebec, Canada, 4 Brain Imaging Center, Montreal Neurological Institute, Quebec, Canada, 5 Biomedical Engineering, McGill University, Quebec, Canada, 6 Montreal Neurological Institute, Quebec, Canada

This study examines the variability in the location of task-based fMRI activation and compares these results with resting-state fMRI based target localization. The result suggests that using a predefined anatomical atlas coordinates for surgical targeting may not be accurate. But, using a combination of resting-state and task-based fMRI can reliably map somatotopy in the thalamus and somatosensory cortex and hence improve target identification for neurosurgery of deep brain structures.

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