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Abstract #0565

Pulmonary MRI in Neonatal Medicine

Jean A Tkach 1 , Alan H Jobe 2 , Suhas G Kallapur 2 , Jeffrey A Whitsett 2 , Robert J Fleck 1 , Stephanie L Merhar 2 , Charles L Dumoulin 1 , and Jason C Woods 1,3

1 Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States, 2 Neonatology and Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States, 3 Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States

Respiratory pathologies are common in premature infants. Pulmonary MRI h has the potential to provide detailed diagnostic information about pulmonary anatomy and function. In this study, its potential utility in neonatal medicine was evaluated. Two identical small footprint 1.5T MR systems designed for imaging neonates and installation within the neonatal intensive care unit were employed to perform pre-clinical and neonatal pulmonary MRI exams. The results demonstrate the feasibility and utility of this neonatal imaging platform to obtain detailed diagnostic thoracic MRI in the neonate, perform longitudinal studies of normal and abnormal lung development, and to evaluate treatment response to therapy.

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