Assessing Portal Vein Contribution on Hepatic Perfusion based on Arterial Spin Labeling MRI
Xiang He 1 , Serter Gumus 1 , and Kyong Tae Bae 1
Department of Radiology, University of
Pittsburgh, Pittsburgh, PA, United States
Assessment of hemodynamic changes in the liver is
particularly challenging due to the dual blood supply.
The portal vein and hepatic artery contribution are
altered, both globally and regionally, in many liver
diseases. In this study, a FAIR-based pulsed ASL
approach with cardiac gating was adopted to quantify
portal venous fraction in healthy controls. By
accounting for the hemodynamic difference of hepatic
supplying vessels, the proposed approach can separate
the contributions from the portal vein and hepatic
artery. This opens new opportunities to detect global
and regional alterations in hepatic flow pattern in
liver disease patients without contrast agent.
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