Abstract #0359
High-resolution 7T MRI and MRSI in patients with suspected mesial temporal epilepsy
Peter B Barker 1 , Gregory K Bergey 2 , Huong Trinh 3 , Tilak Ratnanather 3 , He Zhu 4 , David Bonekamp 5 , and Doris D.M. Lin 5
1
Radiology, JHU SOM, Baltimore, MD, United
States,
2
Neurology,
JHU SOM, MD, United States,
3
Center
for Imaging Science, JHU, MD, United States,
4
Radiology,
Vanderbilt University, TN, United States,
5
Radiology,
JHU SOM, MD, United States
Although MRI plays an important role in the evaluation
of patients with drug-resistant partial epilepsy, it has
been reported that approximately 30% of patients with
mesial temporal lobe epilepsy (mTLE, the most common
form) have normal scans at 1.5 or 3.0T. This study
investigates the use of high resolution MRI and MRSI at
7.0T for the evaluation of mTLE. Results suggests that
subtle abnormalities may be detected at 7.0T in patients
with scans read as normal at 3T. 7.0T MR may therefore
allow more patients to proceed directly to surgery
without the need for invasive EEG monitoring.
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