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Abstract #0359

High-resolution 7T MRI and MRSI in patients with suspected mesial temporal epilepsy

Peter B Barker 1 , Gregory K Bergey 2 , Huong Trinh 3 , Tilak Ratnanather 3 , He Zhu 4 , David Bonekamp 5 , and Doris D.M. Lin 5

1 Radiology, JHU SOM, Baltimore, MD, United States, 2 Neurology, JHU SOM, MD, United States, 3 Center for Imaging Science, JHU, MD, United States, 4 Radiology, Vanderbilt University, TN, United States, 5 Radiology, JHU SOM, MD, United States

Although MRI plays an important role in the evaluation of patients with drug-resistant partial epilepsy, it has been reported that approximately 30% of patients with mesial temporal lobe epilepsy (mTLE, the most common form) have normal scans at 1.5 or 3.0T. This study investigates the use of high resolution MRI and MRSI at 7.0T for the evaluation of mTLE. Results suggests that subtle abnormalities may be detected at 7.0T in patients with scans read as normal at 3T. 7.0T MR may therefore allow more patients to proceed directly to surgery without the need for invasive EEG monitoring.

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