Abstract #0274
Improved tractography of post mortem human brain at 7T using DWSSFP
Sean Foxley 1 , Saad Jbabdi 1 , Wilfred Lam 1 , Olaf Ansorge 2 , Gwenaelle Douaud 1 , and Karla Miller 1
1
FMRIB Centre, University of Oxford, Oxford,
OXON, United Kingdom,
2
University
of Oxford, Oxford, OXON, United Kingdom
Post-mortem human brain imaging at 3T using
diffusion-weighted steady state free precession (DWSSFP)
has been demonstrated to provide improved data for
tractography compared with diffusion weighted spin echo
data. Here, DWSSFP was used to acquire diffusion data of
post-mortem human brain at 7T. Tractography results
produced from this data demonstrated increased
prevalence of secondary fiber estimates compared with
equivalent data acquired at 3T. Better estimates from 7T
data provided improved results in tracts that encounter
intersecting pathways; specifically those that project
through the centrum semiovale. These projecting tracts
detected in 7T data are largely unseen in 3T data.
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