Abstract #0190
Cardiac MR Elastography: Estimation of myocardial stiffness throughout cardiac cycle as a function of age
Peter A Wassenaar 1 , Chethanya N Eleswarpu 1 , Richard D White 1 , and Arunark Kolipaka 1
1
Radiology, The Ohio State University,
Columbus, Ohio, United States
Myocardial stiffness has been a significant biomarker
for various cardiovascular disease processes, such as
myocardial infarction, hypertension, diastolic
dysfunction and tissue rejection in heart transplant
patients. Pressure/volume based techniques are commonly
used to measure left ventricular chamber stiffness, but
are limited to global measurements, are invasive, and do
not provide true intrinsic properties of the myocardium.
Recently, Cardiac MR Elastography was used to estimate
stiffness of the myocardium. In this study, a retrogated,
multi-phase MRE sequence was developed and used to
measure LV myocardial stiffness across the cardiac cycle
as a function of age in healthy subjects.
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