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Abstract #0152

Sodium MRI of Articular Cartilage with Improved SNR Using Coherent SSFP Imaging at 7T

Stefan Zbyn 1 , Oliver Bieri 2 , Vladimir Mlynarik 1 , Vladimir Juras 1 , and Siegfried Trattnig 1

1 High Field MR Centre, Department of Biomedical Imaging and Image-Guided Therapy, Medical University Vienna, Vienna, Austria, 2 Division of Radiological Physics, Department of Radiology, University of Basel Hospital, Basel, Switzerland

Coherent steady state sequences, such as FISP or TrueFISP, may provide higher SNR than spoiled gradient echo (SPGR). However, to our best knowledge, they have not yet been investigated for in vivo 23Na-MRI. In this study, in vivo and ex vivo knee measurements at 7T were performed to assess optimal measurement parameters for FISP and TrueFISP, and to evaluate their SNR compared to SPGR. FISP and TrueFISP provided significantly higher SNR than SPGR in cartilage, muscle and blood. The higher SNR may be traded off for higher resolution or shorter measurement times and help to get 23Na-MRI into clinical practice.

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