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Abstract #0151

Diagnostic performance of a 3D FSE T2 and T1rho sequence for quantitative mapping of articular cartilage composition for the detection of morphological internal knee derangements

Edwin H. Oei 1,2 , Weitian Chen 3 , Jason L. Dragoo 4 , and Garry E. Gold 1,5

1 Radiology, Stanford University, Stanford, California, United States, 2 Radiology, Erasmus MC, Rotterdam, ZH, Netherlands, 3 GE Healthcare, Menlo Park, California, United States, 4 Orthopaedic Surgery, Stanford University, Stanford, California, United States, 5 Bioengineering, Stanford University, Stanford, California, United States

Although quantitative MRI for articular cartilage composition shows promise for early detection of osteoarthritis (OA), large-scale application is hampered by long scan times if added to routine MRI protocols. We assessed the performance of a quantitative 3D FSE T2 and T1rho mapping sequence to diagnose cruciate ligament and meniscal tears, bone marrow lesions, and cartilage defects. For anterior cruciate ligament and medial meniscal tears, diagnostic performance of the 3D FSE T1rho mapping sequence was good and superior to T2 mapping. This sequence may be used to replace routine clinical pulse sequences, enhancing scan time efficiency and potentially accelerating large-scale implementation.

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