Osteoarthritis (OA) is a debilitating disease characterized by joint structural degradation. Meniscal breakdown is linked to OA progression and can be studied through T2 relaxometry. In this work, we assess the effect of acute exercise on meniscus T2 relaxation times in individuals with OA. 12 individuals were scanned before and after performing a single-legged exercise. T2 relaxation times were computed using a qDESS sequence. We found that acute exercise did not affect the meniscal T2 values in OA subjects; however, significant changes in the maximal regional T2 change after exercise were observed that may be impacted by knee loading.
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