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Abstract #4205

Lumbar Fatty Acid Composition (FAC) Measurement in Osteoporosis Patients Using MRI      

Lina Lin1, Lutian Bai1, Qun Cheng2, Manuel Schneider3, Marcel Dominik Nickel3, Caixia Fu4, Guangwu Lin1, and Shihong Li1
1Department of Radiology, Huadong Hospital, Fudan University, Shanghai, China, 2Department of Osteoporosis, Huadong Hospital, Fudan University, Shanghai, China, 3MR Application Predevelopment, Siemens Healthcare GmbH, Erlangen, Germany, 4Application Development, Siemens Shenzhen Magnetic Resonance Ltd, Shenzhen, China

This study is to explore the application value of fatty acid composition (FAC) measurements in the diagnosis of osteoporosis. 39 subjects who underwent dual-energy X-ray absorptiometry (DXA) and lumbar magnetic resonance imaging on a 3T scanner were included. We found that FF value was negatively correlated with T value (P < 0.05, r = -0.371), and SF value was positively correlated with T value (P < 0.05, r = 0.399). The PUF value of the osteopenia group was significantly higher than that of the osteoporosis group（P < 0.05）and normal bone mass group（P < 0.05）.

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