Paramagnetic deoxyhemoglobin introduces magnetic susceptibility to venous vessels in the brain, causing intra-voxel dephasing of surrounding tissue, appearing dark on a susceptibility-weighted image (SWI). However, empirical studies quantifying the extent of this dephasing is lacking. Using time-of-flight (TOF) angiogram as ground truth, and focusing on the straight sinus, we quantified the extent to which SWI vessel diameters deviated from true (TOF) vessel diameters. We find straight sinus diameter based on SWI segmentation to be nearly twice the diameter of TOF segmentation, and the difference between SWI and TOF straight sinus diameter was dependent on vessel location in the y-axis.
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