This study compared
the reading of three radiologists with different level of experience, and also investigated
the potential of deep learning to differentiate between benign and malignant
vertebral fractures based on T1W and T2W MRI. The results showed that deep
learning using ResNet50 achieved a satisfactory diagnostic accuracy of 92%,
although inferior to 98% made by a senior MSK radiologist and 96% made by a R4
resident, much higher compared to 66% made by a R1 resident. The inferior
performance of ResNet50 might be partly explained by the very limited
information when only considering a small bounding box.
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