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Abstract #4009

An MR-Tracked Metallic injection needle for Distancing Radiation-sources from Sensitive tissues: Construct and Initial testing in Swine

Ehud Jeruham Schmidt1, Marc Morcos2, Anthony Gunderman3, Junichi Tokuda4, Ravi Teja Seethamraju5, Luca Neri1, Carmen Kut2, Henry R. Halperin1, Akila Ninette Viswanathan2, and Yue Chen3
1Medicine (Cardiology), Johns Hopkins School of Medicine, Baltimore, MD, United States, 2Radiation Oncology, Johns Hopkins School of Medicine, Baltimore, MD, United States, 3Mechanical Engineering, University of Arkansas, Fayetteville, AR, United States, 4Radiology, Brigham and Women's Hospital, Boston, MA, United States, 5Siemens Medical Solutions, Boston, MA, United States

A metallic actively-tracked injection needle was constructed for purposes of reducing dose to normal tissues surrounding irradiated tumors in cervical cancer and prostate cancer radiation therapy. Hydrogel is injected into tissue or anatomic cavities between the tumor and normal tissues, increasing the distance from the radiation source. The needle was tested in a gynecological phantom and in swine. It provided 1.2x1.2x1.2mm3 targeting precision @16 frames-per-second navigation, supporting rapid navigation speeds currently possible only under X-ray or Ultrasound guidance. The injected topology over time was visualized during injection, allowing creation of more uniform dose-shielding regions.

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Abstract