Swallowing dysfunction (dysphagia) is a common problem and a major cause of morbidity in patients who have undergone radiotherapy for head and neck cancer. However, the pathophysiological basis of dysphagia in these patients is poorly understood and may differ between patients, creating a barrier to developing effective treatment strategies. Improved (and ideally quantitative) methods for characterising swallow function are therefore needed. We describe a method for imaging and analysis of pharyngeal and laryngeal motion during the swallow, based on joint image registration and modelling of intensity changes over a dynamic image series.
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