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Abstract #3883

Multi-parametric functional and structural assessment of the placenta at late gestational ages using MRI  

Daphna Link1, Netanell Avisdris1,2, Xingfeng Shao3, Liat Ben-Sira4,5, Leo Joskowicz2, Ilan Gull6, Danny J.J Wang3, and Dafna Ben-Bashat1,5
1Sagol Brain Institute, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, 2School of Computer Science and Engineering, The Hebrew University of Jerusalem, Jerusalem, Israel, 3Laboratory of FMRI Technology (LOFT), USC Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States, 4Division of Pediatric Radiology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, 5Sackler Faculty of Medicine & Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel, 6Ultrasound Unit, Lis Maternity Hospital, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel

Early and accurate placental insufficiency assessment is of a great importance. Here we comprehensively assessed placental perfusion and structure, and fetal brain and body volumes, in normal fetuses and in cases with fetal growth restriction (FGR) caused by placental insufficiency, at late gestational ages (GA=31-34 weeks). Increased Placental Blood Flow and Arterial Transit Time were detected in normal cases compared to earlier GA reported previously. Significant differences were found in several placental and fetal characteristics between normal and FGR cases. This study emphasizes the importance of multi-parametric assessment of fetuses to enable identification of high risks for FGR.

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Abstract