Abstract #3743

Reproducibility of White Matter Parcellation on Multi-Acquisition Diffusion Weighted Imaging

Stefan Winzeck^1,2, Ben Glocker¹, Virginia F. J. Newcombe², David K. Menon², and Marta M. Correia³

¹BioMedIA, Department of Computing, Imperial College London, London, United Kingdom, ²Division of Anaesthesia, Department of Medicine, University of Cambridge, Cambridge, United Kingdom, ³MRC Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, United Kingdom

The comparison of TractSeg and JHU atlas-based white matter parcellation on DWI showed the impact of different acquisition schemes on both region volumes and variation in diffusion metrics. TractSeg defined fibre bundles more accurately, but volumes varied for different DWI parameters. The atlas-based segmentation of fibre tracts was more robust to acquisition differences, but showed higher variation in diffusion metrics suggesting a less precise differentiation of white and grey matter.

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