No major reports have been evaluated the capability for the molecular-based assessment by 3D chemical exchange saturation transfer (CEST) imaging and compared with 2D CEST imaging. We hypothesized that 3D CEST imaging had equal or better potential for the molecular-based assessment in various brain tumor patients, when compared with 2D CEST imaging. The purpose of this study was to directly compare the capability for molecular-based assessment between 2D and 3D CEST imaging in patients with various brain tumors.
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