Abstract #3703

The value of Amide Proton Transfer weighted and Dynamic Contrast-Enhanced imaging in peritumoral edema assisted grading of gliomas

Xinying Ren¹, Yujing Li¹, Rui Wang¹, Tao Wen¹, Diaohan Xiong¹, Pengfei Wang¹, Guangyao Liu¹, Jing Zhang¹, and Kai Ai²

¹Department of Magnetic Resonance, Lanzhou University Second Hospital, Lanzhou, China, ²Philips Healthcare, Xi'an, China

The study was to quantitatively analyze the peritumoral infiltration assisted gliomas grading by using amide proton transfer (APT) and dynamic contrast-enhanced imaging (DCE). Although many scholars use APT and DCE to help grading gliomas, but few of them pay attention to the peritumoral area. This research investigated the relationship between APT and DCE based K^trans value in peritumoral. The results show that these two parameters are significantly correlated. Therefore, the APT and K^trans value of peritumor edema in gliomas may be used to differentiate glioma grades, and APT value performs better in distinguishing grade Ⅱ and Ⅲ.

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