Meeting Banner
Abstract #3623

Microstructural CMR imaging in a longitudinal pig model of acute to chronic myocardial infarction

Christian T Stoeck1, Constantin von Deuster1, Maximilian Fuetterer1, Malgorzata Polacin1,2, Conny F Waschkies1, Robbert JH van Gorkum1, Mareike Kron3, Thea Fleischmann3, Nikola Cesarovic3,4, Miriam Weisskopf3, and Sebastian Kozerke1
1Institute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland, 2Institute of Diagnostic and Interventional Radiology, University Hospital Zurich, Zurich, Switzerland, 3Division of Surgical Research, University Hospital Zurich, Zurich, Switzerland, 4Institute of Translational Cardiovascular Technologies, ETH Zurich, Zurich, Switzerland

In this work we compare non-contrast enhanced imaging methods such as native T1, T2 mapping and cardiac diffusion tensor imaging, to ECV measurements in a longitudinal porcine study of myocardial infarction. T2 is elevated only during the acute stage. During the transition from acute to chronic stage T1 remains unchanged and ECV as well as MD progressively increase while FA decreases. During the acute stage, T2 mapping provides highest contrast whereas diffusional metrics showed larger changes during the chronic stage compared to native relaxometry showing the potential of DTI for probing dynamic myocardial changes upon an ischemic event.

This abstract and the presentation materials are available to members only; a login is required.

Join Here