Abstract #3598

Free-breathing, motion-resolved myocardial T1 mapping using inversion-recovery radial FLASH and model-based reconstruction

Xiaoqing Wang^1,2, Sebastian Rosenzweig^1,2, Moritz Blumenthal¹, Zhengguo Tan^1,2, Nick Scholand^1,2, and Martin Uecker^1,2,3,4

¹University Medical Center Göttingen, Göttingen, Germany, ²Partner Site Göttingen, German Centre for Cardiovascular Research (DZHK), Göttingen, Germany, ³Cluster of Excellence "Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells" (MBExC), University of Göttingen, Göttingen, Germany, ⁴Campus Institute Data Science (CIDAS), University of Göttingen, Göttingen, Germany

In this work, we develop a motion-resolved model-based reconstruction for free-breathing multi-phase myocardial T1 mapping using a free-running inversion-recovery radial FLASH sequence. Initial results on an experimental phantom and two healthy subjects have demonstrated that the proposed method could achieve motion-resolved T1 mapping at a spatial resolution of 1.33 × 1.33 × 6 mm³ with good accuracy, precision and reproducibility.

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