Chemical shift-encoded (CSE) MRI allows for measurement of important tissue parameters with established and emerging quantitative MRI applications, including proton density fat fraction (PDFF) and R2*. Respiratory and bulk patient movement can affect the accuracy and precision of CSE-MRI measurements, which makes rapid and motion robust imaging of high clinical value. This work demonstrates the combination of simultaneous multislice (SMS) imaging to accelerate 2D motion robust CSE-MRI acquisitions. Results with computer simulations and in vivo experiments confirm the feasibility of combining these two techniques to achieve rapid, whole-liver, motion robust quantitative tissue characterization.
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