Abstract #3207

Distinguishing malignant and benign lung lesions with multiparametric 18F-FDG PET/MRI: Comparison of metabolic parameters and IVIM parameters

Fangfang Fu¹, Nan Meng², Zhun Huang³, Yaping Wu¹, Pengyang Feng³, Xiaochen Li¹, Yan Bai¹, Wei Wei¹, Jianmin Yuan⁴, Tianyi Xu⁴, and Meiyun Wang¹

¹Department of Medical Imaging, Henan Provincial People’s Hospital, People’s Hospital of Zhengzhou University, Zhengzhou, China, ²Department of Radiology, Zhengzhou University People’s Hospital & Henan Provincial People’s Hospital, Academy of Medical Sciences, Zhengzhou, China, ³Department of Radiology, Henan University People’s Hospital & Henan Provincial People’s Hospital, School of Basic Medicine. Department of Radiology, Zhengzhou University People’s Hospital & Henan Provincial People’s Hospital, Academy of Medical Sciences., Zhengzhou, China, ⁴2258 Chengbei Road, Jiading District, Shanghai, China 201907, Shanghai, China

Distinguishing malignant from benign pulmonary lesions is critical. In the study, 18F-FDG PET/MRI were used to obtain metabolic parameters and IVIM diffusion parameters for differential diagnosis of benign and malignant lung lesions. Our results showed that multiparametric PET/MRI is helpful in the differentiation of pulmonary lesions. 18 FDG hybrid PET-MRI enables a robust differentiation of malignant and benign pulmonary lesions when several IVIM parameters and PET parameters are combined. Thus, PET-MRI may reduce some unnecessary lung biopsies.

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