Abstract #3094

Fast and quiet MPRAGE using a silent gradient axis at 7T – subject experience and qualitative image assessment

Sarah M Jacobs¹, Edwin Versteeg¹, Leonie NC Visser², Anja G van der Kolk^1,3, Dennis WJ Klomp¹, and Jeroen CW Siero^1,4

¹Department of Radiology and Nuclear Medicine, University Medical Center Utrecht, Utrecht, Netherlands, ²Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, Netherlands, ³Department of Radiology, the Netherlands Cancer Institute, Amsterdam, Netherlands, ⁴Spinoza Centre for Neuroimaging Amsterdam, Amsterdam, Netherlands

Acoustic noise can negatively impact patients from anxiety and communication problems to transient and permanent hearing loss. In this pilot study we used a silent gradient axis that is switched at the inaudible frequency of 20 kHz with a silent readout module implemented in an MPRAGE sequence, and investigated subject experience and image quality of fast and quiet anatomical brain imaging at 7T. Here we show preliminary evidence that our silent gradient axis with silent readout module incorporated into a T₁-weighted MPRAGE sequence is perceived more quiet and positive and delivers images of largely acceptable quality.

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