Abstract #3052

Fast-Sweep Frequency-Modulated SSFP: Boosting Sensitivity for 3D Joint T1/T2 Mapping

Volkert Roeloffs¹, Nick Scholand^1,2, and Martin Uecker^1,2,3

¹Institute for Diagnostic and Interventional Radiology, University Medical Center Göttingen, Goettingen, Germany, ²DZHK (German Centre for Cardiovascular Research), Partner Site Göttingen, Germany, Goettingen, Germany, ³Campus Institute Data Science (CIDAS), University of Göttingen, Göttingen, Germany, Goettingen, Germany

Sensitivity to T1 and T2 in frequency-modulated SSFP sequences can be increased by choosing a higher modulation speed without prolonging the repetition time. In this work, we assess the boost in sensitivity by Cramér-Rao-bound analysis, combine the sequence with stack-of-stars sampling and subspace-constrained reconstruction, and demonstrate joint T1/T2/B1/off-resonance mapping in phantom and in vivo study. The results render fast-sweep frequency-modulated SSFP an excellent candidate for comprehensive 3D multi-parametric mapping.

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