This study is designed to assess the changes of articular cartilage volume, thickness and T2* value before and after marathon in non-professional athletes by semi-automatic cartilage segmentation prototype software.All volunteers underwent MR scan before and after marathon and accepted follow-up observation.We confirmed that MR biochemical imaging combined with morphological changes can be used to assess the internal structure and general changes of cartilage. The anterior part of medial tibial plateau may be a high risk area for cartilage degeneration under the long-distance marathon.
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