Imaging of knee cartilage is of enormous significance, particularly for patients with osteoarthritis (OA). In this work, we applied Glycosaminoglycans-weighted Chemical Exchange Saturation Transfer (GagCEST) magnetic resonance imaging (MRI) at 7 Telsa (7T) to OA and healthy patients. GagCEST MRI revealed an increase in GagCEST (%) values for control patients in comparison to OA patients and can serve as a sensitive molecular biomarker for quantifying early metabolic changes in cartilage.
This abstract and the presentation materials are available to members only; a login is required.