Abstract #2913

Comparison of 2D-EPI, 3D-EPI and ERASE in terms of physiological noise, SNR and tSNR

Jae-Kyun Ryu^1,2 and Jang-Yeon Park^2,3,4

¹Biomedical Institute for Convergence at SKKU, Sungkyunkwan University, Suwon, Korea, Republic of, ²Center for Neuroscience Imaging Research, Institute for Basic Science, Suwon, Korea, Republic of, ³Department of Biomedical Engineering, Sungkyunkwan University, Suwon, Korea, Republic of, ⁴Department of Intelligent Precision Healthcare Convergence, Sungkyunkwan University, Suwon, Korea, Republic of

Recently we proposed an ultrafast 3D gradient-echo imaging sequence using spatiotemporal-encoding (SPEN), called ERASE (Equal-TE Rapid Acquisition with Sequential Excitation), which has high tolerance to B₀ inhomogeneities. Here, we investigated the noise characteristics, SNR, and tSNR of ERASE with rat brain imaging at 9.4T at high spatial resolution, in comparison with 2D and 3D gradient-echo EPI. While ERASE provided better tSNR than both of them, it provided intermediate SNR between them. The ratio of physiological and thermal noise (σ_P/σ₀) and lambda (λ) were smaller in ERASE than 2D and 3D-EPI mainly due to its robustness against B₀ inhomogeneity.

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