Although sensitivity encoding (SENSE) technique is commonly used to reduce distortion in diffusion-weighted imaging (DWI), highly accelerated SENSE results in significantly increased noise, leading to systematic errors to the quantification of apparent diffusion coefficient. In this study, we proposed a novel method using compressed sensing combined with a highly accelerated sensitivity encoding (CS-SENSE) to reduce both the distortion and noise in liver DWI. The CS-SENSE demonstrated the higher SNR and reduced geometric distortion compared with conventional SENSE reconstruction. Liver DWI with the proposed method can improve the image quality with better lesion conspicuity.
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